Compatible with sterile water for injection or 0.9% sodium chloride
Therapeutic Class
Beta-lactam antibiotic with beta-lactamase inhibitor
Composition
Piperacillin and Tazobactam
Dosage Route
Intravenous (IV) use only
Shelf Life
2 Years
Availability
Single dose vial
Form
Injection
Usage/Application
Hospital, Clinical
Indications
Severe infections, hospital-acquired infections, intra-abdominal infections, skin and soft tissue infections, pneumonia
Packaging Type
Vial
Prescription/Non prescription
Prescription
Administration
Administer by slow IV infusion over 30 minutes
Storage Condition
Store below 25°C, protect from light and moisture
Stability After Reconstitution
Use within 24 hours if stored at 2-8°C
Strength
4.5 g
About Piperacellin Tazobactam injection
Piperacillin and tazobactam is a combination antibiotic commonly used to treat a wide range of bacterial infections. Piperacillin is a broad-spectrum penicillin antibiotic that targets bacterial cell wall synthesis, while tazobactam is a beta-lactamase inhibitor that protects piperacillin from bacterial enzymes that would otherwise degrade it. This combination is effective against infections caused by Gram-positive and Gram-negative bacteria, including pneumonia, urinary tract infections, intra-abdominal infections, and skin infections. It's often used in hospital settings for serious or resistant infections, such as sepsis or complicated intra-abdominal infections, and is generally administered intravenously for optimal effect.
Broad-Spectrum Antibiotic Therapy
Piperacillin Tazobactam injection provides broad-spectrum coverage against a wide range of bacteria, including resistant strains, due to the combination of piperacillin and the beta-lactamase inhibitor tazobactam. This makes it highly effective for severe and complicated infections in hospitals or clinical settings, ensuring optimal outcomes in critical care.
Optimized Intravenous Administration
Designed for intravenous infusion, this medication ensures precise and rapid delivery in acute scenarios. It should be diluted with sterile water for injection or 0.9% sodium chloride, then slowly infused over 30 minutes for maximum efficacy and minimized risk of adverse reactions. Strict adherence to preparation and administration guidelines supports patient safety.
Safe Storage and Stability
The injection should be stored below 25C, shielded from direct light and moisture to maintain potency. After reconstitution, it remains stable for up to 24 hours if refrigerated at 2-8C. Proper storage and handling are essential to preserve its effectiveness and ensure consistent therapeutic results.
FAQ's of Piperacellin Tazobactam injection:
Q: How is Piperacillin Tazobactam injection administered?
A: Piperacillin Tazobactam injection is administered intravenously. After reconstituting the powder with compatible sterile water for injection or 0.9% sodium chloride, the medication should be delivered by slow infusion over a period of 30 minutes to ensure safety and effectiveness.
Q: What infections can be treated with Piperacillin Tazobactam injection?
A: This medication is indicated for the treatment of severe infections such as hospital-acquired infections, intra-abdominal infections, skin and soft tissue infections, and pneumonia. Its broad antimicrobial activity makes it suitable for complicated and resistant infections.
Q: When should the reconstituted injection be used after preparation?
A: After reconstitution, Piperacillin Tazobactam injection should be used within 24 hours if stored at 2-8C in order to maintain its potency and minimize the risk of contamination.
Q: Where should Piperacillin Tazobactam injection be stored before use?
A: The vial should be stored below 25C, and protected from light and moisture. Once reconstituted, any unused solution must be kept in a refrigerator (2-8C) and discarded if not used within 24 hours.
Q: What is the process for preparing Piperacillin Tazobactam injection for administration?
A: To prepare the injection, add the specified amount of sterile water for injection or 0.9% sodium chloride to the vial, gently mix until fully dissolved, and then administer the solution by slow intravenous infusion over 30 minutes.
Q: What is the primary benefit of Piperacillin Tazobactam injection?
A: The main benefit of this injection is its ability to effectively combat a broad spectrum of bacteria, including resistant strains, due to the synergistic action of piperacillin and tazobactam, making it a valuable choice for the management of serious infections in clinical settings.
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